Development and Evaluation of Antimicrobial Activity of Durva Nishadi Ointment: In-vitro Study

Background: Synthetic antimicrobials are often associated with adverse effects as a result, there is need for the use of alternate herbal medicines increasing their easy availability, safety, cost effectiveness and therapeutic potentiality. In this present study Durva Nishadi Ointment was developed from nishadi Yoga described in Ayurvedic classics Lepa (topical application) against microbial diseases like Kandu (Pruritis), Pama (Scabies), Dadru (Tinea/ Ringworm infection), Sheetapitta (Urticarial rashes) Krimi (Microbial infections).
 Result: The ointment has highly significant antifungal activity than antibacterial activity. Antifungal 20% Candida albicans 28mm zone inhibition at 25 μg/ ml, Aspergillus niger 15 mm 5 which comparable synthetic standard drug used i.e. Fluconazole.
 
 Abbreviations
 MIC - Minimum inhibitory concentration, MHA Muller-Hinton Agar